ID1

Across TCGA cell cohorts, ID1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,339 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ID1-associated GO terms across cancer lineages are Circadian rhythm, Schwann cell development, and Negative regulation of mRNA splicing, via spliceosome. Each is linked with ID1 in more than 11 cancer types. Because this analysis shows association rather than direction, both ID1-to-partner and partner-to-ID1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Circadian rhythm grouped by ID1-low versus ID1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ID1→partner) and Y-score (partner→ID1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Circadian rhythm →	+0.081	+1.605	<.001	.001	3	12
OESOPHAGUS	Schwann cell development →	+0.135	+2.208	.001	<.001	3	11
LARGE_INTESTINE	Negative regulation of mRNA splicing, via spliceosome →	+0.075	+1.720	.003	.009	2	10
STOMACH	Regulation of pattern recognition receptor signaling pathway →	+0.054	+1.688	<.001	.003	3	9
BONE	Negative regulation of toll-like receptor signaling pathway →	+0.114	+3.102	<.001	<.001	3	9
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.128	+1.696	.003	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,339 associations by consensus.

Circadian rhythm by ID1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →