ID1

Across TCGA cell cohorts, ID1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ID1-associated genes across cancer lineages are OR11H1, KRTAP13-4, and PPP1R2C. Each is linked with ID1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ID1-to-partner and partner-to-ID1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H1 grouped by ID1-low versus ID1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ID1→partner) and Y-score (partner→ID1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR11H1 →	+0.045	+5.201	.002	.006	3	1
BLOOD_Leukemia	KRTAP13-4 →	+0.025	+5.539	<.001	.003	3	1
BLOOD_Lymphoma	PPP1R2C →	+0.404	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	TECTB →	+0.063	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	C10orf53 →	+0.038	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	DPPA5 →	+0.208	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

OR11H1 by ID1 expression — BLOOD_Leukemia

Explore this box plot interactively →