ICE2P2

Across TCGA patient cohorts, ICE2P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,308 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ICE2P2-associated GO terms across cancer lineages are Regulation of mRNA catabolic process, RNA modification, and Negative regulation of DNA recombination. Each is linked with ICE2P2 in more than 13 cancer types. Because this analysis shows association rather than direction, both ICE2P2-to-partner and partner-to-ICE2P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA catabolic process grouped by ICE2P2-low versus ICE2P2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ICE2P2→partner) and Y-score (partner→ICE2P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of mRNA catabolic process →	+0.063	+0.072	<.001	<.001	3	14
ESCA	RNA modification →	+0.065	+0.080	<.001	.002	3	14
STAD	Negative regulation of DNA recombination →	+0.054	+0.071	<.001	<.001	3	13
STAD	Protein localization to chromosome, telomeric region →	+0.073	+0.072	<.001	<.001	3	13
STAD	Lipoprotein metabolic process →	+0.064	+0.071	<.001	<.001	3	13
ESCA	Ribosomal small subunit biogenesis →	+0.084	+0.108	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,308 associations by consensus.

Regulation of mRNA catabolic process by ICE2P2 expression — STAD

Explore this box plot interactively →