ICE2

Across TCGA patient cohorts, ICE2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,913 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ICE2-associated proteins across cancer lineages are RTF1, ANP32A, and ZNF609. Each is linked with ICE2 in more than 7 cancer types. Because this analysis shows association rather than direction, both ICE2-to-partner and partner-to-ICE2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ICE2 versus RTF1 in GBM, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ICE2→partner) and Y-score (partner→ICE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RTF1 →	+0.304	+0.392	<.001	<.001	3	8
OV	ANP32A →	+0.549	+0.377	<.001	<.001	3	8
LSCC	ZNF609 →	+0.312	+0.519	<.001	<.001	3	7
GBM	FAM98B →	+0.333	+0.496	<.001	<.001	3	7
GBM	DNAJC17 →	+0.333	+0.324	<.001	.002	3	7
LSCC	CCAR1 →	+0.184	+0.419	.004	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,913 associations by consensus.

ICE2 vs RTF1 — GBM

Explore this scatter interactively →