ICE2

Across TCGA patient cohorts, ICE2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,681 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ICE2-associated genes across cancer lineages are CEP72, CHAF1A, and KAT2A. Each is linked with ICE2 in more than 3 cancer types. Because this analysis shows association rather than direction, both ICE2-to-partner and partner-to-ICE2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ICE2 versus CEP72 in HNSC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ICE2→partner) and Y-score (partner→ICE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CEP72 →	+0.628	+0.250	.004	.001	3	4
HNSC	CHAF1A →	+0.724	+0.262	<.001	.003	3	4
BRCA	KAT2A →	+0.690	+0.159	.001	.009	3	3
LSCC	RPF1 →	+0.452	+0.279	.001	<.001	3	3
BRCA	SNRPF →	+0.506	+0.180	<.001	.001	3	3
LSCC	GTF2A2 →	+0.527	+0.329	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,681 associations by consensus.

ICE2 vs CEP72 — HNSC

Explore this scatter interactively →