ICAM3

Across TCGA patient cohorts, ICAM3 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,280 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ICAM3-associated proteins across cancer lineages are ARHGAP45, ARHGAP9, and ARHGDIB. Each is linked with ICAM3 in more than 9 cancer types. Because this analysis shows association rather than direction, both ICAM3-to-partner and partner-to-ICAM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ICAM3 versus ARHGAP45 in LSCC, with a Pearson correlation of 0.86.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ICAM3→partner) and Y-score (partner→ICAM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARHGAP45 →	+0.669	+0.950	<.001	<.001	3	10
UCEC	ARHGAP9 →	+0.551	+0.792	<.001	<.001	3	10
LSCC	ARHGDIB →	+0.730	+0.903	<.001	<.001	3	10
LSCC	PLEKHO2_T311 →	+0.587	+0.594	<.001	<.001	3	10
GBM	PTPN6 →	+0.659	+0.378	<.001	<.001	3	10
LSCC	PTPN7 →	+0.650	+0.932	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,280 associations by consensus.

ICAM3 vs ARHGAP45 — LSCC

Explore this scatter interactively →