ICAM3

Across TCGA cell cohorts, ICAM3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,163 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ICAM3-associated GO terms across cancer lineages are Regulation of termination of RNA polymerase II transcription, Regulation of termination of DNA-templated transcription, and Glucocorticoid metabolic process. Each is linked with ICAM3 in more than 9 cancer types. Because this analysis shows association rather than direction, both ICAM3-to-partner and partner-to-ICAM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of termination of RNA polymerase II transcription grouped by ICAM3-low versus ICAM3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ICAM3→partner) and Y-score (partner→ICAM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of termination of RNA polymerase II transcription →	-0.165	-1.669	<.001	<.001	3	9
OVARY	Regulation of termination of DNA-templated transcription →	-0.165	-1.669	<.001	<.001	3	9
BONE	Glucocorticoid metabolic process →	+0.320	+1.219	<.001	<.001	3	8
STOMACH	Epigenetic regulation of gene expression →	-0.085	-1.197	<.001	.009	3	8
BONE	5S class rRNA transcription by RNA polymerase III →	-0.158	-1.382	<.001	<.001	3	8
BONE	Regulation of body fluid levels →	+0.082	+1.293	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,163 associations by consensus.

Regulation of termination of RNA polymerase II transcription by ICAM3 expression — OVARY

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