ICAM2

Across TCGA patient cohorts, ICAM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,501 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ICAM2-associated proteins across cancer lineages are RCSD1, ARHGAP45, and PECAM1. Each is linked with ICAM2 in more than 7 cancer types. Because this analysis shows association rather than direction, both ICAM2-to-partner and partner-to-ICAM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ICAM2 versus RCSD1 in OV, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ICAM2→partner) and Y-score (partner→ICAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RCSD1 →	+0.699	+0.645	.001	.004	3	8
LSCC	ARHGAP45 →	+0.643	+0.763	<.001	<.001	3	8
LSCC	PECAM1 →	+0.545	+0.675	<.001	<.001	3	8
OV	SASH3 →	+0.620	+0.824	<.001	<.001	3	7
GBM	LCP1 →	+0.827	+0.355	<.001	.001	3	7
OV	LIMD2 →	+1.142	+0.897	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,501 associations by consensus.

ICAM2 vs RCSD1 — OV

Explore this scatter interactively →