ICAM2

Across TCGA patient cohorts, ICAM2 protein abundance is significantly associated with the RNA expression of many other genes, with 19,046 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ICAM2-associated genes across cancer lineages are P2RY8, CLEC1A, and PIK3CG. Each is linked with ICAM2 in more than 7 cancer types. Because this analysis shows association rather than direction, both ICAM2-to-partner and partner-to-ICAM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ICAM2 versus P2RY8 in OV, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ICAM2→partner) and Y-score (partner→ICAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	P2RY8 →	+1.001	+0.486	<.001	.001	3	8
CCRCC	CLEC1A →	+0.846	+0.466	<.001	<.001	3	7
LSCC	PIK3CG →	+0.992	+0.544	<.001	<.001	3	6
LSCC	P2RX1 →	+1.005	+0.578	<.001	<.001	3	6
LSCC	LY9 →	+0.820	+0.524	<.001	<.001	3	6
LSCC	CPNE5 →	+0.978	+0.572	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,046 associations by consensus.

ICAM2 vs P2RY8 — OV

Explore this scatter interactively →