ICA1

Across TCGA cell cohorts, ICA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,057 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ICA1-associated GO terms across cancer lineages are Cilium or flagellum-dependent cell motility, Membrane bending, and Collagen fibril organization. Each is linked with ICA1 in more than 9 cancer types. Because this analysis shows association rather than direction, both ICA1-to-partner and partner-to-ICA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium or flagellum-dependent cell motility grouped by ICA1-low versus ICA1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ICA1→partner) and Y-score (partner→ICA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cilium or flagellum-dependent cell motility →	-0.096	-2.742	.001	.002	3	10
BREAST	Membrane bending →	+0.191	+2.424	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Collagen fibril organization →	-0.281	-3.093	.003	<.001	3	10
STOMACH	Establishment of epithelial cell apical/basal polarity →	-0.216	-3.305	<.001	<.001	3	10
BREAST	Vesicle localization →	+0.069	+2.734	<.001	<.001	3	10
OESOPHAGUS	Cilium-dependent cell motility →	-0.096	-2.742	.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,057 associations by consensus.

Cilium or flagellum-dependent cell motility by ICA1 expression — OESOPHAGUS

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