IBA57

Across TCGA pan-cancer cohorts, IBA57 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated IBA57 data layer compared with 21 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher IBA57 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated IBA57 expression acts as an unfavorable survival marker, although some lineages such as COAD and CCRCC show a favorable association.

UCEC, COAD, and CCRCC are the cancer types where IBA57 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	0.433	1.000	.007	26	view →
COAD	DFS	Median	II,III,IV	1.000	0.882	.022	24	view →
CCRCC	OS	Tertile	II,III,IV	0.985	0.133	.027	9	view →
LUAD	OS	Median	III,IV	0.376	0.868	.026	4	view →
LSCC	DFS	Quartile	All	0.622	0.859	.029	4	view →
PDAC	DFS	Quartile	All	0.567	0.325	.024	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

IBA57–UCEC (OS)

Open the UCEC breakdown →