IBA57

Across TCGA cell cohorts, IBA57 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IBA57-associated genes across cancer lineages are GRM4, C1QL2, and NAA11. Each is linked with IBA57 in more than 1 cancer types. Because this analysis shows association rather than direction, both IBA57-to-partner and partner-to-IBA57 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GRM4 grouped by IBA57-low versus IBA57-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IBA57→partner) and Y-score (partner→IBA57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GRM4 →	+1.127	+3.491	<.001	.004	3	1
LARGE_INTESTINE	C1QL2 →	+0.004	+3.514	.006	.001	3	1
LARGE_INTESTINE	NAA11 →	+0.347	+3.443	.002	.009	3	1
LARGE_INTESTINE	OR10W1 →	+0.014	+3.562	<.001	.002	3	1
LARGE_INTESTINE	C10orf53 →	+0.010	+3.217	.002	.006	3	1
LARGE_INTESTINE	TAFA1 →	+0.234	+3.103	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

GRM4 by IBA57 expression — LARGE_INTESTINE

Explore this box plot interactively →