IARS2P1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IARS2P1 RNA expression is significantly associated with the protein abundance of many other proteins, with 3,603 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IARS2P1-associated proteins across cancer lineages are ZNF219_S114, ZNF318_S2101, and ZNF768_S139. Each is linked with IARS2P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IARS2P1-to-partner and partner-to-IARS2P1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IARS2P1 versus ZNF219_S114 in GBM, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IARS2P1→partner) and Y-score (partner→IARS2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMZNF219_S114 →+0.718+0.284<.001<.00132
GBMZNF318_S2101 →+0.292+0.269.004.00532
GBMZNF768_S139 →+0.378+0.270.002<.00132
HNSCNCOR2_S2393 →+1.149+0.618<.001.00532
GBMSBF1_S1142 →+0.444+0.402<.001.00132
GBMACSL4 →-0.395-0.309<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,603 associations by consensus.

IARS2P1 vs ZNF219_S114 — GBM

Per-sample scatter of IARS2P1 vs ZNF219_S114 in GBM (Pearson r = 0.30).

Explore this scatter interactively →

Exploration