IARS2P1

Across TCGA patient cohorts, IARS2P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,753 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IARS2P1-associated GO terms across cancer lineages are Telomere maintenance, Embryonic organ morphogenesis, and Maintenance of cell number. Each is linked with IARS2P1 in more than 13 cancer types. Because this analysis shows association rather than direction, both IARS2P1-to-partner and partner-to-IARS2P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere maintenance grouped by IARS2P1-low versus IARS2P1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IARS2P1→partner) and Y-score (partner→IARS2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Telomere maintenance →	+0.080	+0.102	<.001	<.001	3	14
ESCA	Embryonic organ morphogenesis →	+0.042	+0.100	<.001	.001	3	12
STAD	Maintenance of cell number →	+0.067	+0.035	<.001	<.001	3	12
ESCA	Regulation of microtubule-based process →	+0.066	+0.109	<.001	<.001	3	12
STAD	Import into nucleus →	+0.071	+0.035	<.001	<.001	3	12
ESCA	Regulation of proteasomal protein catabolic process →	+0.079	+0.100	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,753 associations by consensus.

Telomere maintenance by IARS2P1 expression — ESCA

Explore this box plot interactively →