IAH1

Across TCGA pan-cancer cohorts, IAH1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated IAH1 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher IAH1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated IAH1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

PDAC, CCRCC, and LSCC are the cancer types where IAH1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Quartile	All	0.627	0.323	.002	40	view →
CCRCC	DFS	Tertile	II,III,IV	0.904	0.105	.008	16	view →
LSCC	DFS	Tertile	II,III,IV	0.449	0.844	.012	16	view →
UCEC	DFS	Quartile	All	0.923	0.683	.018	12	view →
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →
LUAD	DFS	Quartile	All	1.000	0.560	.019	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

IAH1–PDAC (OS)

Open the PDAC breakdown →