IAH1

Across TCGA cell cohorts, IAH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,218 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible IAH1-associated GO terms across cancer lineages are Ribosome biogenesis, Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), and Fatty acid beta-oxidation using acyl-CoA oxidase. Each is linked with IAH1 in more than 6 cancer types. Because this analysis shows association rather than direction, both IAH1-to-partner and partner-to-IAH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosome biogenesis grouped by IAH1-low versus IAH1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IAH1→partner) and Y-score (partner→IAH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Ribosome biogenesis →	-0.114	-1.045	<.001	.003	3	7
BONE	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	-0.102	-0.911	.002	.003	3	7
LUNG_SCLC	Fatty acid beta-oxidation using acyl-CoA oxidase →	+0.092	+0.755	<.001	<.001	3	7
BONE	'de novo' AMP biosynthetic process →	-0.146	-0.966	.001	.001	3	7
BONE	Positive regulation of telomere maintenance via telomere lengthening →	-0.086	-0.872	<.001	<.001	3	6
BONE	rRNA processing →	-0.118	-1.159	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,218 associations by consensus.

Ribosome biogenesis by IAH1 expression — BONE

Explore this box plot interactively →