HYMAI

Across TCGA patient cohorts, HYMAI RNA expression is significantly associated with the protein abundance of many other proteins, with 10,306 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible HYMAI-associated proteins across cancer lineages are CDH1, GSPT1, and AP1M2. Each is linked with HYMAI in more than 3 cancer types. Because this analysis shows association rather than direction, both HYMAI-to-partner and partner-to-HYMAI results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HYMAI versus CDH1 in HNSC, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HYMAI→partner) and Y-score (partner→HYMAI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CDH1 →	-0.347	-0.577	.002	<.001	3	4
HNSC	GSPT1 →	-0.263	-0.592	<.001	<.001	3	4
BRCA	AP1M2 →	-0.351	-0.136	<.001	.002	3	4
COAD	SEC23B →	-0.255	-0.141	.002	<.001	3	4
LSCC	EPN3 →	-0.578	-0.339	<.001	.002	3	4
UCEC	FERMT2 →	+0.512	+0.656	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,306 associations by consensus.

HYMAI vs CDH1 — HNSC

Explore this scatter interactively →