Across TCGA patient cohorts, HYLS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,732 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HYLS1-associated proteins across cancer lineages are SMC2, RRM2, and CCNB1. Each is linked with HYLS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both HYLS1-to-partner and partner-to-HYLS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HYLS1→partner) and Y-score (partner→HYLS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SMC2 →	+0.525	+0.586	<.001	<.001	3	8
OV	RRM2 →	+0.728	+0.969	<.001	<.001	3	7
UCEC	CCNB1 →	+0.679	+0.616	<.001	.004	3	7
OV	CDK1 →	+0.800	+0.780	<.001	<.001	3	7
BRCA	MCM3 →	+0.579	+0.552	<.001	<.001	2	8
OV	NDC80 →	+0.703	+0.716	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,732 associations by consensus.

Exploration

HYLS1 survival (RNA) · tumor vs normal (RNA) · all HYLS1 data types