Across TCGA cell cohorts, HYLS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,173 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HYLS1-associated GO terms across cancer lineages are Regulation of chromosome separation, Negative regulation of chromosome segregation, and Mitotic spindle assembly checkpoint signaling. Each is linked with HYLS1 in more than 11 cancer types. Because this analysis shows association rather than direction, both HYLS1-to-partner and partner-to-HYLS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HYLS1→partner) and Y-score (partner→HYLS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of chromosome separation →	+0.145	+0.825	<.001	.007	3	12
URINARY_TRACT	Negative regulation of chromosome segregation →	+0.136	+1.108	.001	.004	3	11
BREAST	Mitotic spindle assembly checkpoint signaling →	+0.143	+1.241	<.001	<.001	3	11
BREAST	Spindle assembly checkpoint signaling →	+0.143	+1.241	<.001	<.001	3	11
BREAST	Mitotic spindle checkpoint signaling →	+0.143	+1.241	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of mitotic sister chromatid separation →	+0.117	+0.892	.002	.002	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,173 associations by consensus.

Exploration

HYLS1 survival (RNA) · tumor vs normal (RNA) · all HYLS1 data types