HYI

Across TCGA patient cohorts, HYI RNA expression is significantly associated with the go_rna of many other GO terms, with 7,164 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible HYI-associated GO terms across cancer lineages are Positive regulation of DNA repair, Positive regulation of double-strand break repair, and DNA modification. Each is linked with HYI in more than 26 cancer types. Because this analysis shows association rather than direction, both HYI-to-partner and partner-to-HYI results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by HYI-low versus HYI-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HYI→partner) and Y-score (partner→HYI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Positive regulation of DNA repair →	+0.038	+0.767	<.001	<.001	3	27
DLBC	Positive regulation of double-strand break repair →	+0.049	+0.739	<.001	<.001	2	27
THYM	DNA modification →	+0.051	+0.436	<.001	<.001	3	26
KIRC	Protein deacetylation →	+0.048	+0.803	<.001	<.001	3	26
KIRC	Protein methylation →	+0.038	+0.714	<.001	<.001	3	26
SCLC	Positive regulation of stem cell population maintenance →	+0.097	+0.524	<.001	.004	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,164 associations by consensus.

Positive regulation of DNA repair by HYI expression — DLBC

Explore this box plot interactively →