HYI

Across TCGA cell cohorts, HYI RNA expression is significantly associated with the go_rna of many other GO terms, with 4,573 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HYI-associated GO terms across cancer lineages are Glyoxylate metabolic process, Positive regulation of anaphase-promoting complex-dependent catabolic process, and PML body organization. Each is linked with HYI in more than 18 cancer types. Because this analysis shows association rather than direction, both HYI-to-partner and partner-to-HYI results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glyoxylate metabolic process grouped by HYI-low versus HYI-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HYI→partner) and Y-score (partner→HYI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Glyoxylate metabolic process →	+0.354	+1.872	<.001	<.001	3	19
BONE	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.125	+0.997	.006	.002	3	12
LUNG_NSCLC_LUSC	PML body organization →	+0.215	+1.760	<.001	<.001	3	11
OVARY	Positive regulation of fibroblast proliferation →	+0.129	+1.483	.001	.001	3	10
LUNG_NSCLC_LUSC	Protein lipidation →	+0.087	+1.827	.006	.001	3	10
BREAST	Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration →	+0.140	+1.200	.003	.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,573 associations by consensus.

Glyoxylate metabolic process by HYI expression — BLOOD_Myeloma

Explore this box plot interactively →