Across TCGA pan-cancer cohorts, HYAL6P Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated HYAL6P data layer compared with 15 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher HYAL6P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated HYAL6P expression acts as an unfavorable survival marker.

ESCA and UCEC are the cancer types where HYAL6P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	All	0.022	0.701	<.001	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: HYAL6P tumor-vs-normal RNA expression · all HYAL6P data types