Across TCGA patient cohorts, HYAL3 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,573 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HYAL3-associated proteins across cancer lineages are ALG5, PHPT1, and NKTR_S463. Each is linked with HYAL3 in more than 3 cancer types. Because this analysis shows association rather than direction, both HYAL3-to-partner and partner-to-HYAL3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HYAL3→partner) and Y-score (partner→HYAL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ALG5 →	-0.367	-0.452	.001	.008	3	4
LSCC	PHPT1 →	-0.350	-0.789	<.001	<.001	3	4
LSCC	NKTR_S463 →	+0.474	+0.634	.001	.001	3	4
LSCC	MYDGF →	-0.422	-0.670	<.001	<.001	3	3
HNSC	ACACA →	+0.258	+0.803	.003	<.001	2	4
GBM	PARP4 →	-0.418	-0.435	.008	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,573 associations by consensus.

Exploration

HYAL3 survival (RNA) · tumor vs normal (RNA) · all HYAL3 data types