HYAL3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HYAL3 mutation is significantly associated with the RNA expression of many other genes, with 621 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HYAL3-associated genes across cancer lineages are MIR4295, RNU6-128P, and LINC01400. Each is linked with HYAL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both HYAL3-to-partner and partner-to-HYAL3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HYAL3→partner) and Y-score (partner→HYAL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAMIR4295 →+0.727+5.112<.001.00132
BLCARNU6-128P →+0.305+5.018.002.00432
HNSCLINC01400 →+0.073+5.124.001.00832
SKCMRNA5SP106 →+0.203+4.797<.001.00332
UCECRNU6-859P →+0.501+2.123<.001.00932
UCECRNA5SP379 →+0.614+2.425<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 621 associations by consensus.

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