Across TCGA cell cohorts, HYAL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,512 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HYAL3-associated GO terms across cancer lineages are Penetration of zona pellucida, Negative regulation of ovarian follicle development, and Regulation of acrosomal vesicle exocytosis. Each is linked with HYAL3 in more than 19 cancer types. Because this analysis shows association rather than direction, both HYAL3-to-partner and partner-to-HYAL3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HYAL3→partner) and Y-score (partner→HYAL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Penetration of zona pellucida →	+1.829	+2.239	<.001	<.001	3	20
PANCREAS	Negative regulation of ovarian follicle development →	+1.238	+1.433	<.001	<.001	3	17
PANCREAS	Regulation of acrosomal vesicle exocytosis →	+0.714	+1.266	.003	<.001	3	9
STOMACH	Regulation of amine transport →	-0.122	-0.807	<.001	.001	3	8
SOFT_TISSUE	GDP-mannose biosynthetic process →	+0.108	+0.760	<.001	<.001	3	7
LARGE_INTESTINE	Regulation of non-motile cilium assembly →	+0.091	+0.726	.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,512 associations by consensus.

Exploration

HYAL3 survival (RNA) · tumor vs normal (RNA) · all HYAL3 data types