HYAL2

Across TCGA patient cohorts, HYAL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,561 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible HYAL2-associated proteins across cancer lineages are VWF, ESAM, and ERG_S81. Each is linked with HYAL2 in more than 5 cancer types. Because this analysis shows association rather than direction, both HYAL2-to-partner and partner-to-HYAL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HYAL2 versus VWF in CCRCC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HYAL2→partner) and Y-score (partner→HYAL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	VWF →	+0.505	+0.905	<.001	<.001	3	6
CCRCC	ESAM →	+0.576	+1.054	<.001	<.001	3	5
CCRCC	ERG_S81 →	+0.925	+1.017	<.001	<.001	3	5
CCRCC	VCL_S346 →	+0.566	+0.973	<.001	<.001	3	4
BRCA	NES_T851 →	+0.737	+0.689	.002	<.001	3	4
LSCC	PDK1 →	-0.515	-0.374	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,561 associations by consensus.

HYAL2 vs VWF — CCRCC

Explore this scatter interactively →