HYAL2

Across TCGA patient cohorts, HYAL2 mutation is significantly associated with the RNA expression of many other genes, with 224 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HYAL2-associated genes across cancer lineages are SNX3P1Y, SRIP3, and MIR1302-8. Each is linked with HYAL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HYAL2-to-partner and partner-to-HYAL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNX3P1Y grouped by HYAL2-low versus HYAL2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HYAL2→partner) and Y-score (partner→HYAL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNX3P1Y →	+0.104	+4.571	<.001	.002	3	2
UCEC	SRIP3 →	+0.434	+2.332	.004	.001	3	2
SKCM	MIR1302-8 →	+0.603	+3.893	<.001	.004	3	2
LUAD	ZNF736P3Y →	+0.049	+7.930	<.001	.008	3	2
COAD	NAGPA-AS1 →	+0.123	+5.020	<.001	<.001	3	2
UCEC	LINC00294 →	+0.469	+2.928	.005	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 224 associations by consensus.

SNX3P1Y by HYAL2 expression — UCEC

Explore this box plot interactively →