HYAL2

Across TCGA cell cohorts, HYAL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,560 significant associations in total. CNS shows the largest number of these associations.

The most reproducible HYAL2-associated GO terms across cancer lineages are Renal water transport, Negative regulation of fibroblast migration, and Protein depolymerization. Each is linked with HYAL2 in more than 12 cancer types. Because this analysis shows association rather than direction, both HYAL2-to-partner and partner-to-HYAL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Renal water transport grouped by HYAL2-low versus HYAL2-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HYAL2→partner) and Y-score (partner→HYAL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Renal water transport →	+1.136	+0.913	<.001	.002	3	13
SOFT_TISSUE	Negative regulation of fibroblast migration →	+0.188	+0.895	<.001	<.001	3	12
SKIN	Protein depolymerization →	+0.128	+0.932	<.001	<.001	2	12
KIDNEY	Regulation of Wnt protein secretion →	+0.148	+0.868	.005	.009	3	11
CNS	Positive regulation of early endosome to late endosome transport →	+0.105	+0.600	<.001	.001	3	11
BLOOD_Leukemia	Renal water absorption →	+0.854	+0.694	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,560 associations by consensus.

Renal water transport by HYAL2 expression — BLOOD_Myeloma

Explore this box plot interactively →