HUNK

Across TCGA cell cohorts, HUNK RNA expression is significantly associated with the go_rna of many other GO terms, with 3,927 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible HUNK-associated GO terms across cancer lineages are Positive regulation of DNA repair, Regulation of DNA repair, and Negative regulation of mRNA metabolic process. Each is linked with HUNK in more than 11 cancer types. Because this analysis shows association rather than direction, both HUNK-to-partner and partner-to-HUNK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by HUNK-low versus HUNK-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HUNK→partner) and Y-score (partner→HUNK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of DNA repair →	+0.083	+2.531	<.001	<.001	3	12
LIVER	Regulation of DNA repair →	+0.068	+1.630	<.001	.001	3	12
OESOPHAGUS	Negative regulation of mRNA metabolic process →	+0.089	+0.480	.003	.001	3	11
STOMACH	Positive regulation of myoblast differentiation →	+0.141	+1.465	.001	<.001	3	11
LUNG_SCLC	Regulation of G0 to G1 transition →	+0.155	+2.442	<.001	<.001	3	11
BLOOD_Lymphoma	Positive regulation of double-strand break repair via homologous recombination →	+0.087	+0.693	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,927 associations by consensus.

Positive regulation of DNA repair by HUNK expression — LUNG_SCLC

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