HUNK-AS1

Across TCGA pan-cancer cohorts, HUNK-AS1 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated HUNK-AS1 data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher HUNK-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated HUNK-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and LUSC show a favorable association.

LGG, KIRC, and UVM are the cancer types where HUNK-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	OS	Median	All	0.730	0.889	<.001	32	view →
KIRC	DFS	Tertile	III,IV	0.739	0.389	.020	24	view →
UVM	DFS	Tertile	All	0.210	0.761	.011	18	view →
LIHC	DFS	Tertile	All	0.271	0.560	.023	18	view →
SKCM	DFS	Tertile	II,III,IV	0.105	0.237	.026	12	view →
CHOL	DFS	Tertile	II,III,IV	0.118	0.458	.026	9	view →
LUSC	OS	Tertile	II,III,IV	0.868	0.720	.023	9	view →
STAD	DFS	Tertile	IV	0.160	0.402	.044	9	view →
SARC	OS	Tertile	All	0.913	0.810	.007	9	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

HUNK-AS1–LGG (OS)

Open the LGG breakdown →