HTR6

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HTR6 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,292 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HTR6-associated proteins across cancer lineages are GABPA, RPS8_S160, and RPS8_T130. Each is linked with HTR6 in more than 3 cancer types. Because this analysis shows association rather than direction, both HTR6-to-partner and partner-to-HTR6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HTR6 versus GABPA in LSCC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HTR6→partner) and Y-score (partner→HTR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCGABPA →+0.199+0.245<.001<.00134
GBMRPS8_S160 →-0.608-0.281.001.00733
HNSCRPS8_T130 →-0.759-0.265<.001<.00133
LUADKAT6A_S1113 →+1.250+0.304<.001.00433
CCRCCANXA2 →-0.365-0.660<.001.00233
HNSCUSP15_S229 →-0.530-0.266<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,292 associations by consensus.

HTR6 vs GABPA — LSCC

Per-sample scatter of HTR6 vs GABPA in LSCC (Pearson r = 0.39).

Explore this scatter interactively →

Exploration