HTR6

Across TCGA cell cohorts, HTR6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,115 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HTR6-associated GO terms across cancer lineages are Nucleoside triphosphate metabolic process, Purine nucleotide biosynthetic process, and Positive regulation of DNA metabolic process. Each is linked with HTR6 in more than 7 cancer types. Because this analysis shows association rather than direction, both HTR6-to-partner and partner-to-HTR6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleoside triphosphate metabolic process grouped by HTR6-low versus HTR6-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HTR6→partner) and Y-score (partner→HTR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Nucleoside triphosphate metabolic process →	+0.072	+0.232	<.001	.002	3	7
LARGE_INTESTINE	Purine nucleotide biosynthetic process →	+0.051	+0.161	<.001	.008	3	7
SKIN	Positive regulation of DNA metabolic process →	+0.040	+0.198	.003	.002	2	8
OVARY	Viral translational termination-reinitiation →	+0.053	+0.237	.002	.007	3	6
BREAST	tRNA transcription →	+0.093	+0.277	<.001	<.001	3	6
BREAST	Negative regulation of transcription initiation by RNA polymerase II →	+0.114	+0.229	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,115 associations by consensus.

Nucleoside triphosphate metabolic process by HTR6 expression — SKIN

Explore this box plot interactively →