HTR6

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, HTR6 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HTR6-associated genes across cancer lineages are HTR3D. Each is linked with HTR6 in more than 1 cancer types. Because this analysis shows association rather than direction, both HTR6-to-partner and partner-to-HTR6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HTR3D grouped by HTR6-low versus HTR6-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HTR6→partner) and Y-score (partner→HTR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaHTR3D →+0.020+6.247<.001<.00131
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

HTR3D by HTR6 expression — BLOOD_Lymphoma

Box plot of HTR3D in HTR6-low vs HTR6-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration