HTR2B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HTR2B protein abundance is significantly associated with the RNA expression of many other genes, with 1,742 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible HTR2B-associated genes across cancer lineages are RNF43, KLF12, and SDK1. Each is linked with HTR2B in more than 2 cancer types. Because this analysis shows association rather than direction, both HTR2B-to-partner and partner-to-HTR2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HTR2B versus RNF43 in UCEC, with a Pearson correlation of 0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HTR2B→partner) and Y-score (partner→HTR2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNF43 →+2.083+0.962<.001<.00132
UCECKLF12 →+1.544+0.962<.001<.00132
UCECSDK1 →+2.203+1.096<.001<.00132
HNSCNODAL →+2.108+2.200.009<.00132
OVRCE1 →+1.279+1.539.008.00532
UCECRNU6-1263P →+1.711+1.146<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,742 associations by consensus.

HTR2B vs RNF43 — UCEC

Per-sample scatter of HTR2B vs RNF43 in UCEC (Pearson r = 0.81).

Explore this scatter interactively →

Exploration