HTR2B

Across TCGA cell cohorts, HTR2B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,516 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible HTR2B-associated GO terms across cancer lineages are Positive regulation of phosphatidylinositol biosynthetic process, Leading strand elongation, and Late viral transcription. Each is linked with HTR2B in more than 8 cancer types. Because this analysis shows association rather than direction, both HTR2B-to-partner and partner-to-HTR2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of phosphatidylinositol biosynthetic process grouped by HTR2B-low versus HTR2B-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HTR2B→partner) and Y-score (partner→HTR2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Positive regulation of phosphatidylinositol biosynthetic process →	+0.693	+2.056	<.001	<.001	3	9
URINARY_TRACT	Leading strand elongation →	+0.099	+0.148	.001	.003	3	6
LUNG_NSCLC_LUSC	Late viral transcription →	+0.121	+0.153	<.001	.005	3	5
UPPER_AERODIGESTIVE_TRACT	Cortical actin cytoskeleton organization →	+0.086	+0.083	<.001	.004	3	5
BREAST	Establishment of protein localization to organelle →	+0.047	+0.121	<.001	<.001	3	5
BREAST	Oxidative demethylation →	-0.160	-0.109	<.001	<.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,516 associations by consensus.

Positive regulation of phosphatidylinositol biosynthetic process by HTR2B expression — SKIN

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