HTR2A

Across TCGA patient cohorts, HTR2A protein abundance is significantly associated with the RNA expression of many other genes, with 3,049 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HTR2A-associated genes across cancer lineages are RASL10A, NEFH, and SYNGR1. Each is linked with HTR2A in more than 1 cancer types. Because this analysis shows association rather than direction, both HTR2A-to-partner and partner-to-HTR2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HTR2A versus RASL10A in GBM, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HTR2A→partner) and Y-score (partner→HTR2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RASL10A →	+0.653	+0.681	.008	.004	3	1
GBM	NEFH →	+0.928	+0.570	<.001	<.001	3	1
GBM	SYNGR1 →	+0.805	+0.734	<.001	<.001	3	1
GBM	PNPLA5 →	+0.317	+0.900	<.001	<.001	3	1
GBM	CACNA1I →	+0.593	+0.722	<.001	<.001	3	1
GBM	PVALB →	+0.855	+0.648	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,049 associations by consensus.

HTR2A vs RASL10A — GBM

Explore this scatter interactively →