Across TCGA patient cohorts, HTN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,118 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HTN3-associated GO terms across cancer lineages are Negative regulation of protein localization, Axon guidance, and Negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. Each is linked with HTN3 in more than 5 cancer types. Because this analysis shows association rather than direction, both HTN3-to-partner and partner-to-HTN3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HTN3→partner) and Y-score (partner→HTN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of protein localization →	+0.062	+0.050	<.001	<.001	3	5
ESCA	Axon guidance →	+0.035	+0.041	<.001	.004	3	5
STAD	Negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.082	+0.093	<.001	.001	3	4
STAD	Anterior/posterior pattern specification →	+0.049	+0.070	<.001	<.001	3	4
STAD	Negative regulation of homotypic cell-cell adhesion →	+0.043	+0.044	<.001	.002	3	4
STAD	Ventricular cardiac muscle cell development →	+0.062	+0.064	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,118 associations by consensus.

Exploration

HTN3 survival (RNA) · tumor vs normal (RNA) · all HTN3 data types