HTN1

Across TCGA patient cohorts, HTN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,325 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible HTN1-associated GO terms across cancer lineages are Mitotic metaphase chromosome alignment, Positive regulation of cell cycle phase transition, and Aminoglycan metabolic process. Each is linked with HTN1 in more than 7 cancer types. Because this analysis shows association rather than direction, both HTN1-to-partner and partner-to-HTN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic metaphase chromosome alignment grouped by HTN1-low versus HTN1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HTN1→partner) and Y-score (partner→HTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitotic metaphase chromosome alignment →	+0.114	+0.169	<.001	.001	3	7
ESCA	Positive regulation of cell cycle phase transition →	+0.045	+0.043	<.001	.001	3	7
ESCA	Aminoglycan metabolic process →	+0.027	+0.042	<.001	.002	3	7
STAD	Organelle membrane fusion →	+0.057	+0.130	<.001	<.001	3	7
ESCA	Cerebellar cortex morphogenesis →	+0.057	+0.062	<.001	<.001	3	6
ESCA	Substantia nigra development →	+0.072	+0.070	<.001	.005	1	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,325 associations by consensus.

Mitotic metaphase chromosome alignment by HTN1 expression — STAD

Explore this box plot interactively →