HTN1

Across TCGA cell cohorts, HTN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 424 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible HTN1-associated GO terms across cancer lineages are Steroid catabolic process, Epithelial cell-cell adhesion, and Response to mechanical stimulus. Each is linked with HTN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HTN1-to-partner and partner-to-HTN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Steroid catabolic process grouped by HTN1-low versus HTN1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HTN1→partner) and Y-score (partner→HTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Steroid catabolic process →	+0.174	+1.548	<.001	.004	3	2
SKIN	Epithelial cell-cell adhesion →	-0.177	-1.290	<.001	.002	3	2
SKIN	Response to mechanical stimulus →	-0.046	-1.959	<.001	.001	3	2
SKIN	Dendritic cell differentiation →	-0.092	-1.001	<.001	<.001	3	2
SKIN	Regulation of membrane repolarization during action potential →	-0.151	-1.402	<.001	.004	3	2
SKIN	Positive regulation of gliogenesis →	-0.077	-1.356	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 424 associations by consensus.

Steroid catabolic process by HTN1 expression — SKIN

Explore this box plot interactively →