HTATSF1

Across TCGA cell cohorts, HTATSF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,766 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HTATSF1-associated GO terms across cancer lineages are Negative regulation of G2/M transition of mitotic cell cycle, Negative regulation of cell cycle G2/M phase transition, and U2-type prespliceosome assembly. Each is linked with HTATSF1 in more than 15 cancer types. Because this analysis shows association rather than direction, both HTATSF1-to-partner and partner-to-HTATSF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of G2/M transition of mitotic cell cycle grouped by HTATSF1-low versus HTATSF1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HTATSF1→partner) and Y-score (partner→HTATSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Negative regulation of G2/M transition of mitotic cell cycle →	+0.079	+1.341	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle G2/M phase transition →	+0.084	+0.983	.006	.001	3	15
LUNG_SCLC	U2-type prespliceosome assembly →	+0.111	+1.233	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of chromosome condensation →	+0.185	+0.908	.008	.008	2	16
BLOOD_Myeloma	Mitotic G2/M transition checkpoint →	+0.087	+1.248	<.001	.002	3	14
OVARY	Spindle elongation →	+0.187	+0.612	<.001	.004	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,766 associations by consensus.

Negative regulation of G2/M transition of mitotic cell cycle by HTATSF1 expression — BLOOD_Myeloma

Explore this box plot interactively →