HTATSF1

Across TCGA cell cohorts, HTATSF1 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HTATSF1-associated genes across cancer lineages are MMP27, KRT84, and OTUD6A. Each is linked with HTATSF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HTATSF1-to-partner and partner-to-HTATSF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP27 grouped by HTATSF1-low versus HTATSF1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HTATSF1→partner) and Y-score (partner→HTATSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	MMP27 →	+0.026	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	KRT84 →	+0.069	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OTUD6A →	+0.113	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	PRAMEF20 →	+0.415	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	AADACL4 →	+0.022	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	NANOGNB →	+0.038	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

MMP27 by HTATSF1 expression — BLOOD_Lymphoma

Explore this box plot interactively →