HTATSF1

Across TCGA cell cohorts, HTATSF1 mutation is significantly associated with the mutation status of many other genes, with 4,890 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HTATSF1-associated genes across cancer lineages are RTN4, HEATR5B, and TMEM132A. Each is linked with HTATSF1 in more than 3 cancer types. Because this analysis shows association rather than direction, both HTATSF1-to-partner and partner-to-HTATSF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RTN4 grouped by HTATSF1-low versus HTATSF1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HTATSF1→partner) and Y-score (partner→HTATSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	RTN4 →	+3.316	+3.906	.004	.004	1	4
SKIN	HEATR5B →	+3.316	+3.906	.004	.004	1	4
OVARY	TMEM132A →	+4.415	+4.977	.007	.007	1	4
OVARY	MLIP →	+5.415	+5.415	.004	.004	1	4
LUNG_NSCLC_LUAD	CNGA4 →	+4.772	+5.339	.004	.004	1	3
LUNG_NSCLC_LUAD	C10orf90 →	+5.772	+5.772	.002	.002	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,890 associations by consensus.

RTN4 by HTATSF1 expression — SKIN

Explore this box plot interactively →