HTATIP2

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, HTATIP2 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated HTATIP2 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher HTATIP2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated HTATIP2 expression acts as an unfavorable survival marker.

CCRCC, GBM, and LUAD are the cancer types where HTATIP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCOSMedianAll0.7310.943.00158view →
GBMDFSQuartileAll0.2840.559.00117view →
LUADOSMedianAll0.6670.858.0137view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

HTATIP2–CCRCC (OS)

Kaplan–Meier survival curve for HTATIP2 mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration