HSPH1

Across TCGA pan-cancer cohorts, HSPH1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated HSPH1 data layer compared with 25 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher HSPH1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated HSPH1 expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

CCRCC, LUAD, and GBM are the cancer types where HSPH1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	III,IV	0.546	0.839	.009	13	view →
LUAD	DFS	Median	All	0.558	0.875	.032	3	view →
GBM	DFS	Tertile	All	0.826	0.556	.026	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

HSPH1–CCRCC (OS)

Open the CCRCC breakdown →