HSPH1

Across TCGA patient cohorts, HSPH1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,169 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSPH1-associated proteins across cancer lineages are HSPH1_S809, HSPH1_T815, and HSPH1_S557. Each is linked with HSPH1 in more than 7 cancer types. Because this analysis shows association rather than direction, both HSPH1-to-partner and partner-to-HSPH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPH1 versus HSPH1_S809 in HNSC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPH1→partner) and Y-score (partner→HSPH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HSPH1_S809 →	+1.077	+0.960	<.001	<.001	3	8
BRCA	HSPH1_T815 →	+1.022	+0.688	<.001	.003	3	8
LSCC	HSPH1_S557 →	+0.802	+0.727	<.001	<.001	3	6
LSCC	DNAJA1 →	+0.222	+0.555	.002	.006	3	5
GBM	HNRNPH1_S23 →	+0.718	+0.478	<.001	<.001	3	4
BRCA	KPNA3 →	+0.319	+0.589	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,169 associations by consensus.

HSPH1 vs HSPH1_S809 — HNSC

Explore this scatter interactively →