HSPH1

Across TCGA patient cohorts, HSPH1 protein abundance is significantly associated with the RNA expression of many other genes, with 19,227 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible HSPH1-associated genes across cancer lineages are GTF3A, POMP, and MYBL2. Each is linked with HSPH1 in more than 7 cancer types. Because this analysis shows association rather than direction, both HSPH1-to-partner and partner-to-HSPH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPH1 versus GTF3A in UCEC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPH1→partner) and Y-score (partner→HSPH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GTF3A →	+0.555	+0.312	<.001	<.001	3	8
BRCA	POMP →	+0.710	+0.525	<.001	<.001	3	7
BRCA	MYBL2 →	+1.339	+0.366	<.001	<.001	3	6
UCEC	PSMA7 →	+0.789	+0.322	.004	<.001	3	6
HNSC	SWT1 →	-0.484	-0.623	<.001	<.001	3	6
UCEC	EIF2S2 →	+0.854	+0.310	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,227 associations by consensus.

HSPH1 vs GTF3A — UCEC

Explore this scatter interactively →