HSPE1P3

Across TCGA pan-cancer cohorts, HSPE1P3 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of HSPE1P3’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where HSPE1P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HSPE1P3 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

LUAD, LIHC, and UCEC are the cancer types where HSPE1P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HSPE1P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	+0.487	<.001	7	view →
LIHC	All	All	+0.249	<.001	7	view →
UCEC	All	III,IV	+0.627	.014	6	view →
BRCA	All	All	+0.363	<.001	6	view →
KIRC	All	All	+0.167	.005	6	view →
CHOL	All	All	+0.644	<.001	5	view →
HNSC	All	III,IV	+0.241	.001	5	view →
BLCA	Male	All	+0.627	.002	4	view →
COAD	All	II,III,IV	+0.432	.004	4	view →
THCA	Female	All	−0.359	<.001	4	view →
STAD	All	II,III,IV	+0.482	.012	3	view →
PRAD	All	All	+0.308	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

HSPE1P3–LUAD

Open the LUAD breakdown →