heat shock protein family E (Hsp10) member 1 pseudogene 27Genealiases: []
Q-omics provides the consensus-scored HSPE1P27 profile across patient tissues and cancer cell-line models. HSPE1P27 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, HSPE1P27 is differentially expressed in 7, with the highest sampling consensus in HNSC. Additionally, HSPE1P27 RNA expression shows 10,312 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight KIRC, HNSC, and LSCC as cancer lineages where HSPE1P27 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for HSPE1P27 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes HSPE1P27 survival associations across molecular data types. HSPE1P27 RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible HSPE1P27 RNA expression–survival associations across cancer types. High HSPE1P27 expression shows unfavorable associations in KIRC, LUAD, THYM, TGCT, KICH and PRAD. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .008). Together, the overview and detailed table identify KIRC as the clearest survival context for HSPE1P27 RNA expression.
This table summarizes HSPE1P27 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 7. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for HSPE1P27. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. HSPE1P27 shows lower tumor expression in BRCA, COAD and KICH and higher tumor expression in HNSC, STAD and CHOL. The HNSC box plot shows higher HSPE1P27 RNA expression in tumor versus normal tissue (log2 FC = +0.142, t-test p = .002).
This table shows molecular features associated with HSPE1P27 in patient tissues and cancer cell lines. In patient samples, HSPE1P27 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set.
