Across TCGA pan-cancer cohorts, HSPE1P26 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of HSPE1P26’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where HSPE1P26 RNA is repressed in tumor relative to normal tissue. In most cancer types HSPE1P26 is over-expressed in tumor, although a few such as BRCA and KIRP show the opposite, repressed pattern.

BRCA, KIRP, and KIRP are the cancer types where HSPE1P26 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HSPE1P26 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	−0.321	.019	2	view →
KIRP	All	IV	+0.187	.032	2	view →
KIRP	All	II,III,IV	−0.123	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 2 lineages.

Exploration

Same gene, other analysis: HSPE1P26 RNA expression & survival · all HSPE1P26 data types