HSPE1P25

Across TCGA pan-cancer cohorts, HSPE1P25 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of HSPE1P25’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where HSPE1P25 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HSPE1P25 is over-expressed in tumor.

HNSC, BLCA, and LUSC are the cancer types where HSPE1P25 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HSPE1P25 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.114	.010	6	view →
BLCA	All	IV	+0.412	.012	4	view →
LUSC	All	All	+0.099	.006	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

HSPE1P25–HNSC

Open the HNSC breakdown →